Unexplained Fertility Problems: Diagnosis and Fertility Treatment Options

Thousands of couples face infertility problems every year, but in cases where standard infertility testing has not found a specific cause behind the failure to conceive, dealing with unexplained fertility problems can be a frustrating experience. Unexplained infertility, also known as idiopathic infertility, can leave couples wondering whether they will ever have the opportunity to have children.

However, even when a doctor cannot find the reason behind the failure to conceive, many couples can explore fertility treatments such as in vitro fertilization or in vitro maturation. Here’s a close look at some of the generally accepted causes behind unexplained fertility and the different treatment options available:

Probable Causes of Unexplained Fertility

After ruling out the possibility of cancer and general health problems, some of the causes of unexplained fertility may include:
  • Insufficient LH hormones
  • Low quality eggs
  • Immature eggs
  • Insufficient release of hormones from the pituitary gland
  • Embryo fails to divide at a healthy rate
  • Fertilized egg does not divide at all
  • The blastocyst does not hatch out of its shell
  • Underdeveloped endometrial lining of the uterus
  • Insufficient amounts of follicular fluid
These are just some of the probable causes of unexplained fertility in women. Hundreds of molecular and chemical events must take place in order for the egg to be fertilized and for an embryo to develop, and a woman who is dealing with hormonal imbalances or has tissue damage in the uterus will face a number of challenges when trying to conceive.
The diagnosis of unexplained infertility is also much greater in women who are 35 years of age and older. Most women who are over 40 years of age typically have difficulty getting pregnant because of egg related issues.

Treatment Options for Unexplained Infertility

While unexplained infertility is relatively common, there are some fertility treatment options availabl. Many studies have been conducted to support the success of timed intercourse coupled with fertility drugs such as Clomid. This process involves taking Clomid pills (clomiphene citrate) for about three to six months so that the ovaries can begin releasing more eggs each month. Other treatment options for couples dealing with unexplained infertility include:
  • Clomid plus IUI treatments: Studies have shown that treatment with Clomid tablest and IUI treatments can increase success rates by up to 10% per cycle.
  • Fertility drugs such as Letrozole or Femara: These are oral fertility drugs that help to stimulate the development of follicles during the infertility treatment process.
  • FSH hormone treatments: Injectable gonadotropins combined with intrauterine insemination (IUI) can help to increase fertility rates.
  • FSH hormones plus intercourse: Helps increase ovarian stimulation and may help increase the chances of conceiving.
  • Assisted reproductive technologies
  • In vitro fertilization (IVF): This infertility treatment has the highest success rate in young women and is a relatively simple procedure
If you are dealing with unexplained infertility problems, consult with a fertility specialist in your area to discuss different treatment options available. He or she will be able to share the benefits and drawbacks of different procedures and recommend a treatment plan.