Gamete Intrafallopian Transfer (GIFT)


GIFT Overview

If you are experiencing infertility problems such as a tubal blockage, have significant tubal damage, or have anatomical problems with your uterus, a fertility specialist may recommend gamete intrafallopian transfer (GIFT) as an IVF alternative. GIFT is often selected as the best fertility treatment by couples who have failed to conceive for at least the past 12 months of trying, and those who have not responded well or have failed with five to six cycles of ovarian stimulation and intrauterine stimulation.
If you have tubal damage or uterine problems and think you may be a good candidate for GIFT, talk to a fertility specialist in your area. Your IVF doctor may recommend the GIFT treatment as an alternative to other treatments.

The GIFT Procedure

GIFT, or gamete intrafallopian transfer, is an assisted reproductive procedure where eggs are collected through aspiration and then mixed with mobile sperm to increase chances of fertilization. The eggs and sperm are placed in a special catheter and then transferred to the fallopian tubes through a laparascopic procedure. A fertility specialist can determine if pregnancy has occurred by performing a simple blood test. GIFT is different from other fertility treatments, such as in vitro fertilization (IVF) and zygote intrafallopian transfer (ZIFT) because fertilization occurs right inside the fallopian tubes. Fertilization does not take place inside a laboratory, so for some people, this may feel like a more “natural” type of conception.

Advantages of the GIFT Fertility Treatment

Does not involve embryo culture 
Option to pursue additional fertility treatments
Physician selects only the best quality embryos on Day 3 or Day 5 of the transfer
Fertilization occurs inside fallopian tubes, instead of in a laboratory

Disadvantages of the GIFT Fertility Treatment

Requires an extra surgical procedure (laparoscopy)
Couples dealing with male factor infertility may be better candidates for in vitro fertilization (IVF)
Woman needs to take special medications to produce more eggs

Find a GIFT Fertility Specialist in Your Area

Talk to an IVF doctor in your area about the pros and cons of GIFT, and to find out if you are a good candidate for this type of fertility treatment. Your fertility specialist may recommend GIFT or another IVF alternative based on your health history, goals and experiences with various types of fertility treatments.